Anna‐Leigh Brown
Queen Mary University of London(GB)University College London(GB)
Publications by Year
Research Areas
Amyotrophic Lateral Sclerosis Research, RNA Research and Splicing, Neurogenetic and Muscular Disorders Research, Lung Cancer Treatments and Mutations, Genetic Neurodegenerative Diseases
Most-Cited Works
- → TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A(2022)486 cited
- → Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer(2020)174 cited
- → Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer(2021)157 cited
- → The era of cryptic exons: implications for ALS-FTD(2023)138 cited
- → APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors(2019)107 cited
- → Cell environment shapes TDP-43 function with implications in neuronal and muscle disease(2022)50 cited
- → HnRNP K mislocalisation is a novel protein pathology of frontotemporal lobar degeneration and ageing and leads to cryptic splicing(2021)47 cited
- → Unexpected frequency of the pathogenic AR CAG repeat expansion in the general population(2023)27 cited
- → Common ALS/FTD risk variants in UNC13A exacerbate its cryptic splicing and loss upon TDP-43 mislocalization(2021)18 cited
- → NOS1AP is a novel molecular target and critical factor in TDP-43 pathology(2022)14 cited