Irena Sieglová
Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry(CZ)
Publications by Year
Research Areas
Monoclonal and Polyclonal Antibodies Research, Enzyme Structure and Function, Protein Structure and Dynamics, Bacterial Genetics and Biotechnology, RNA Interference and Gene Delivery
Most-Cited Works
- → Design of HIV Protease Inhibitors Based on Inorganic Polyhedral Metallacarboranes(2009)150 cited
- → Coiled Coil Peptides as Universal Linkers for the Attachment of Recombinant Proteins to Polymer Therapeutics(2011)51 cited
- → Polymer Therapeutics with a Coiled Coil Motif Targeted against Murine BCL1 Leukemia(2013)38 cited
- → Crystal structures of the effector‐binding domain of repressor Central glycolytic gene Regulator from Bacillus subtilis reveal ligand‐induced structural changes upon binding of several glycolytic intermediates(2008)35 cited
- → Probing Receptor Specificity by Sampling the Conformational Space of the Insulin-like Growth Factor II C-domain(2016)23 cited
- → The crystal structure of the secreted aspartic protease 1 from Candida parapsilosis in complex with pepstatin A(2009)22 cited
- → Structure of the effector-binding domain of the arabinose repressor AraR fromBacillus subtilis(2012)18 cited
- → Polymer Cancerostatics Targeted by Recombinant Antibody Fragments to GD2-Positive Tumor Cells(2018)18 cited
- → Polymer Cancerostatics Targeted with an Antibody Fragment Bound via a Coiled Coil Motif: In Vivo Therapeutic Efficacy against Murine BCL1 Leukemia(2017)13 cited
- → Thiopurine intolerance-causing mutations in NUDT15 induce temperature-dependent destabilization of the catalytic site(2019)13 cited