Brian B. Lee
University of Florida(US)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Biochemical and Molecular Research, Lung Cancer Treatments and Mutations, Cancer Mechanisms and Therapy, Synthesis and biological activity
Most-Cited Works
- → Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents(2008)407 cited
- → Targeting Activated Akt with GDC-0068, a Novel Selective Akt Inhibitor That Is Efficacious in Multiple Tumor Models(2013)293 cited
- → Discovery and Preclinical Pharmacology of a Selective ATP-Competitive Akt Inhibitor (GDC-0068) for the Treatment of Human Tumors(2012)184 cited
- → An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt(2012)167 cited
- → Abstract 873: Combined targeting of Akt and MEK with the Akt inhibitor GDC-0068 and MEK inhibitor GDC-0973 demonstrates synergistic anti-tumor effects(2012)2 cited
- → P3-87(2006)2 cited
- → Incidental Finding of Splenic Artery Aneurysm on Lumbosacral Spine Radiograph(2011)1 cited
- → Supplementary Figures 1 - 5 from Targeting Activated Akt with GDC-0068, a Novel Selective Akt Inhibitor That Is Efficacious in Multiple Tumor Models(2023)
- → Supplementary Tables 1 - 3 from Targeting Activated Akt with GDC-0068, a Novel Selective Akt Inhibitor That Is Efficacious in Multiple Tumor Models(2023)
- → Opposing roles for myeloid and smooth muscle cell STING in pulmonary hypertension(2025)