Louis J. Bedell
Pfizer (United States)(US)
Publications by Year
Research Areas
Peptidase Inhibition and Analysis, Protease and Inhibitor Mechanisms, Chemical Synthesis and Analysis, Monoclonal and Polyclonal Antibodies Research, T-cell and B-cell Immunology
Most-Cited Works
- → Orally Active MMP-1 Sparing α-Tetrahydropyranyl and α-Piperidinyl Sulfone Matrix Metalloproteinase (MMP) Inhibitors with Efficacy in Cancer, Arthritis, and Cardiovascular Disease(2010)97 cited
- → Synthesis and Biological Evaluation of Novel 2,4-Diaminoquinazoline Derivatives as SMN2 Promoter Activators for the Potential Treatment of Spinal Muscular Atrophy(2008)92 cited
- → Synthesis and Structure−Activity Relationships of β- and α-Piperidine Sulfone Hydroxamic Acid Matrix Metalloproteinase Inhibitors with Oral Antitumor Efficacy(2005)64 cited
- → α-Amino-β-sulphone hydroxamates as potent MMP-13 inhibitors that spare MMP-1(2001)37 cited
- → Synthesis and activity of selective MMP inhibitors with an aryl backbone(2000)28 cited
- → Design of MHC class II (DR4) ligands using conformationally restricted imino acids at p3 and p5(1996)24 cited
- → Selective, orally active MMP inhibitors with an aryl backbone(2001)17 cited
- → Discovery of novel leukotriene A4 hydrolase inhibitors based on piperidine and piperazine scaffolds(2010)11 cited
- → MMP-13 selective alpha-sulfone hydroxamates: Identification of selective P1′ amides(2011)10 cited
- → A Peptidomimetic that Specifically Inhibits Human Leukocyte Antigen DRB1*0401-restricted T Cell Proliferation(1997)10 cited