Mary Thorncroft
Publications by Year
Research Areas
DNA Repair Mechanisms, Cancer-related Molecular Pathways, Cancer Genomics and Diagnostics, Glioma Diagnosis and Treatment, Epigenetics and DNA Methylation
Most-Cited Works
- Germ-line mutations of TP53 in Li-Fraumeni families: an extended study of 39 families.(1997)
- → Are There Low-Penetrance TP53 Alleles? Evidence from Childhood Adrenocortical Tumors(1999)262 cited
- → Alkylpurine–DNA–N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients(2011)171 cited
- → Flipping of alkylated DNA damage bridges base and nucleotide excision repair(2009)128 cited
- → A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours(2011)125 cited
- → A detailed study of loss of heterozygosity on chromosome 17 in tumours from Li – Fraumeni patients carrying a mutation to the TP53 gene(1997)105 cited
- → Temozolomide Pharmacodynamics in Patients with Metastatic Melanoma: DNA Damage and Activity of Repair Enzymes O6-Alkylguanine Alkyltransferase and Poly(ADP-Ribose) Polymerase-1(2005)103 cited
- → An extended Li-Fraumeni kindred with gastric carcinoma and a codon 175 mutation in TP53.(1995)83 cited
- → Allelic imbalance of chromosome 6q in ovarian tumours(1995)74 cited
- → Characterization of germline TP53 splicing mutations and their genetic and functional analysis(2001)62 cited