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Philippe de Médina | doi.page

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Philippe de Médina

Centre National de la Recherche Scientifique(FR)Inserm(FR)Centre de Recherche en Cancérologie de Toulouse(FR)

Publications by Year

Research Areas

Cholesterol and Lipid Metabolism, Estrogen and related hormone effects, Cancer, Lipids, and Metabolism, Steroid Chemistry and Biochemistry, Hormonal Regulation and Hypertension

Most-Cited Works

→ Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins(2010)620 cited
→ Identification of a tumor-promoter cholesterol metabolite in human breast cancers acting through the glucocorticoid receptor(2017)122 cited
→ Identification and pharmacological characterization of cholesterol-5,6-epoxide hydrolase as a target for tamoxifen and AEBS ligands(2010)120 cited
→ Dendrogenin A arises from cholesterol and histamine metabolism and shows cell differentiation and anti-tumour properties(2013)116 cited
→ Dendrogenin A drives LXR to trigger lethal autophagy in cancers(2017)103 cited
→ Molecular Characterization of the Microsomal Tamoxifen Binding Site(2004)96 cited

→ MAPK14/p38α confers irinotecan resistance to TP53-defective cells by inducing survival autophagy(2012)

95 cited

→ Tamoxifen and AEBS ligands induced apoptosis and autophagy in breast cancer cells through the stimulation of sterol accumulation(2009)90 cited

→ Multiple Targeting by the Antitumor Drug Tamoxifen: A Structure-Activity Study(2004)80 cited

→ Ligands of the antiestrogen-binding site induce active cell death and autophagy in human breast cancer cells through the modulation of cholesterol metabolism(2009)80 cited