Gianni Chessari
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Computational Drug Discovery Methods, Peptidase Inhibition and Analysis, ATP Synthase and ATPases Research, Protease and Inhibitor Mechanisms
Most-Cited Works
- → Diverse, High-Quality Test Set for the Validation of Protein−Ligand Docking Performance(2007)634 cited
- → Recent Developments in Fragment-Based Drug Discovery(2008)605 cited
- → Modeling Water Molecules in Protein−Ligand Docking Using GOLD(2005)388 cited
- → Discovery of (2,4-Dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a Novel Inhibitor of the Molecular Chaperone Hsp90 by Fragment Based Drug Design(2010)261 cited
- → Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine β-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency(2007)211 cited
- → From fragment to clinical candidate—a historical perspective(2009)196 cited
- → Fragment-Based Drug Discovery Applied to Hsp90. Discovery of Two Lead Series with High Ligand Efficiency(2010)185 cited
- → Trisubstituted Acridine Derivatives as Potent and Selective Telomerase Inhibitors(2003)183 cited
- → Application of Fragment Screening by X-ray Crystallography to β-Secretase(2007)144 cited
- → Application of Fragment Screening by X-ray Crystallography to the Discovery of Aminopyridines as Inhibitors of β-Secretase(2007)142 cited