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I‐Jen Chen | doi.page

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I‐Jen Chen

Ministry of Health and Welfare(TW)National Cheng Kung University(TW)

Publications by Year

Research Areas

Computational Drug Discovery Methods, Protein Structure and Dynamics, Cell death mechanisms and regulation, Microbial Natural Products and Biosynthesis, Microwave Engineering and Waveguides

Most-Cited Works

→ The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models(2016)1,037 cited
→ Drug-like Bioactive Structures and Conformational Coverage with the LigPrep/ConfGen Suite: Comparison to Programs MOE and Catalyst(2010)200 cited
→ An ultra-weak chemiluminescence study on oxidative stress in rabbits following acute thermal injury(1998)166 cited
→ Combined ab initio/empirical approach for optimization of Lennard‐Jones parameters for polar‐neutral compounds(2001)122 cited
→ Polymer Melt Flow Instabilities in Extrusion: Investigation of the Mechanism and Material and Geometric Variables(1971)121 cited
→ Time-Dependent Stress in Polymer Melts and Review of Viscoelastic Theory(1972)118 cited
→

Lessons for fragment library design: analysis of output from multiple screening campaigns

(2009)

118 cited

→ Drug-like Annotation and Duplicate Analysis of a 23-Supplier Chemical Database Totalling 2.7 Million Compounds(2004)114 cited

→ S55746 is a novel orally active BCL-2 selective and potent inhibitor that impairs hematological tumor growth(2018)109 cited

→ Conformational Sampling of Druglike Molecules with MOE and Catalyst: Implications for Pharmacophore Modeling and Virtual Screening(2008)108 cited