Paula Kaplan‐Lefko
University of California, Los Angeles(US)
Publications by Year
Research Areas
CAR-T cell therapy research, Virus-based gene therapy research, Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, Cancer, Hypoxia, and Metabolism
Most-Cited Works
- → Pathobiology of autochthonous prostate cancer in a pre‐clinical transgenic mouse model(2003)434 cited
- → PD-1 Blockade Expands Intratumoral Memory T Cells(2016)401 cited
- → Adoptive Transfer of MART-1 T-Cell Receptor Transgenic Lymphocytes and Dendritic Cell Vaccination in Patients with Metastatic Melanoma(2014)250 cited
- → Safety, Pharmacokinetics, and Pharmacodynamics of AMG 102, a Fully Human Hepatocyte Growth Factor–Neutralizing Monoclonal Antibody, in a First-in-Human Study of Patients with Advanced Solid Tumors(2010)159 cited
- → Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase(2008)139 cited
- → c-Met Inhibitors with Novel Binding Mode Show Activity against Several Hereditary Papillary Renal Cell Carcinoma-related Mutations(2007)137 cited
- → Conatumumab, a fully human agonist antibody to death receptor 5, induces apoptosis via caspase activation in multiple tumor types(2010)125 cited
- → Discovery of a Potent, Selective, and Orally Bioavailable c-Met Inhibitor: 1-(2-Hydroxy-2-methylpropyl)-N-(5-(7-methoxyquinolin-4-yloxy)pyridin-2-yl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (AMG 458)(2008)94 cited
- → Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer(2019)92 cited
- → A Pilot Trial of the Combination of Transgenic NY-ESO-1–reactive Adoptive Cellular Therapy with Dendritic Cell Vaccination with or without Ipilimumab(2018)92 cited