An Vandemeulebroucke
Roche (Switzerland)(CH)
Publications by Year
Research Areas
Biochemical and Molecular Research, HIV/AIDS drug development and treatment, Trypanosoma species research and implications, Adenosine and Purinergic Signaling, Enzyme Structure and Function
Most-Cited Works
- → Leaving Group Activation by Aromatic Stacking: An Alternative to General Acid Catalysis(2004)89 cited
- → Substrate-assisted Leaving Group Activation in Enzyme-catalyzed N-Glycosidic Bond Cleavage(2005)32 cited
- → Kinetic and Chemical Mechanism of the Dihydrofolate Reductase from Mycobacterium tuberculosis(2010)30 cited
- → Evolution of the Chemical Step in Enzyme Catalysis(2021)26 cited
- → A Flexible Loop as a Functional Element in the Catalytic Mechanism of Nucleoside Hydrolase from Trypanosoma vivax(2008)23 cited
- → Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors(2009)23 cited
- → Structure and Mechanism of the 6-Oxopurine Nucleosidase from Trypanosoma brucei brucei,(2010)21 cited
- → Pre-Steady-State Analysis of the Nucleoside Hydrolase of Trypanosoma vivax. Evidence for Half-of-the-Sites Reactivity and Rate-Limiting Product Release(2003)19 cited
- → Multiple Transients in the Pre-Steady-State of Nucleoside Hydrolase Reveal Complex Substrate Binding, Product Base Release, and Two Apparent Rates of Chemistry(2006)15 cited
- → Kinetic Consequences of Introducing a Proximal Selenocysteine Ligand into Cytochrome P450cam(2015)14 cited