William H. Chappell
University of North Carolina at Chapel Hill(US)Becton Dickinson (United States)(US)East Carolina University(US)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Melanoma and MAPK Pathways, Cancer-related Molecular Pathways, Cancer Mechanisms and Therapy, Synthesis and biological activity
Most-Cited Works
- → Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance(2006)2,275 cited
- → Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging(2011)695 cited
- → Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Inhibitors: Rationale and Importance to Inhibiting These Pathways in Human Health(2011)575 cited
- → Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance(2012)315 cited
- → Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response.(2012)302 cited
- → Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy(2011)261 cited