Susan M. Lotarski
Pfizer (United States)(US)
Publications by Year
Research Areas
Neuroscience and Neuropharmacology Research, Receptor Mechanisms and Signaling, Ion channel regulation and function, Nicotinic Acetylcholine Receptors Study, Pharmacological Receptor Mechanisms and Effects
Most-Cited Works
- → Behavioral Characterization of A53T Mice Reveals Early and Late Stage Deficits Related to Parkinson’s Disease(2013)186 cited
- → Negative allosteric modulation of metabotropic glutamate receptor 5 results in broad spectrum activity relevant to treatment resistant depression(2012)85 cited
- → Discovery of the Potent and Selective M1 PAM-AgonistN-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects(2016)83 cited
- → Positive Allosteric Modulation of AMPA Receptors from Efficacy to Toxicity: The Interspecies Exposure-Response Continuum of the Novel Potentiator PF-4778574(2013)61 cited
- → Design and Synthesis of γ- and δ-Lactam M1 Positive Allosteric Modulators (PAMs): Convulsion and Cholinergic Toxicity of an M1-Selective PAM with Weak Agonist Activity(2017)58 cited
- → Anxiolytic-Like Activity of Pregabalin in the Vogel Conflict Test in α2δ-1 (R217A) and α2δ-2 (R279A) Mouse Mutants(2011)52 cited
- → Novel Cyclopropyl β-Amino Acid Analogues of Pregabalin and Gabapentin That Target the α2-δ Protein(2005)45 cited
- → Design and optimization of selective azaindole amide M1 positive allosteric modulators(2015)44 cited
- → Synthesis of a Series of 4-Benzyloxyaniline Analogues as Neuronal N-Type Calcium Channel Blockers with Improved Anticonvulsant and Analgesic Properties(1999)41 cited
- → Anticonvulsant activity of pregabalin in the maximal electroshock-induced seizure assay in α2δ1 (R217A) and α2δ2 (R279A) mouse mutants(2014)33 cited