Ryan P. Wurz
Amgen (United States)(US)
Publications by Year
Research Areas
Cyclopropane Reaction Mechanisms, Crystallization and Solubility Studies, Protein Kinase Regulation and GTPase Signaling, X-ray Diffraction in Crystallography, Cancer Mechanisms and Therapy
Most-Cited Works
- → Discovery of a Covalent Inhibitor of KRASG12C (AMG 510) for the Treatment of Solid Tumors(2019)691 cited
- → Catalytic Asymmetric Synthesis of Piperidine Derivatives through the [4 + 2] Annulation of Imines with Allenes(2005)375 cited
- → Chiral Dialkylaminopyridine Catalysts in Asymmetric Synthesis(2007)336 cited
- → Photoinduced, Copper-Catalyzed Decarboxylative C–N Coupling to Generate Protected Amines: An Alternative to the Curtius Rearrangement(2017)318 cited
- → TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation(2011)228 cited
- → Doubly Activated Cyclopropanes as Synthetic Precursors for the Preparation of 4-Nitro- and 4-Cyano-dihydropyrroles and Pyrroles(2005)212 cited
- → A “Click Chemistry Platform” for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation(2017)199 cited
- → Transition Metal-Catalyzed Cyclopropanation of Alkenes in Water: Catalyst Efficiency and in Situ Generation of the Diazo Reagent(2002)114 cited
- → An Expedient and Practical Method for the Synthesis of a Diverse Series of Cyclopropane α-Amino Acids and Amines(2004)113 cited
- → Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation(2023)112 cited