Eduardo L. Setti
Brandywine Photonics (United States)(US)Aptose Biosciences (United States)(US)
Publications by Year
Research Areas
Carbohydrate Chemistry and Synthesis, Phenothiazines and Benzothiazines Synthesis and Activities, Synthesis of β-Lactam Compounds, Antibiotic Resistance in Bacteria, Protease and Inhibitor Mechanisms
Most-Cited Works
- → Design and Synthesis of Tri-Ring P3 Benzamide-Containing Aminonitriles as Potent, Selective, Orally Effective Inhibitors of Cathepsin K(2005)94 cited
- → A Novel Class of Nonpeptidic Biaryl Inhibitors of Human Cathepsin K(2003)82 cited
- → Identification of 1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea Hydrochloride (CEP-32496), a Highly Potent and Orally Efficacious Inhibitor of V-RAF Murine Sarcoma Viral Oncogene Homologue B1 (BRAF) V600E(2011)58 cited
- → 3,4-Disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P2 elements for selectivity(2003)56 cited
- → β-Substituted Cyclohexanecarboxamide: A Nonpeptidic Framework for the Design of Potent Inhibitors of Cathepsin K(2006)36 cited
- → 3,4-Disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P3 elements for potency and selectivity(2005)29 cited