Arthur M. Doweyko
Bristol-Myers Squibb (United States)(US)
Publications by Year
Research Areas
Computational Drug Discovery Methods, Melanoma and MAPK Pathways, Synthesis and biological activity, Estrogen and related hormone effects, Chemical Synthesis and Analysis
Most-Cited Works
- → Discovery of N-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays(2004)1,285 cited
- → 2-Aminothiazole as a Novel Kinase Inhibitor Template. Structure−Activity Relationship Studies toward the Discovery of N -(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a Potent pan -Src Kinase Inhibitor(2006)395 cited
- → Antiulcer Agents. 6. Analysis of the in Vitro Biochemical and in Vivo Gastric Antisecretory Activity of Substituted Imidazo[1,2-a]pyridines and Related Analogues Using Comparative Molecular Field Analysis and Hypothetical Active Site Lattice Methodologies(1997)196 cited
- → In silico ADME/Tox: why models fail(2003)175 cited
- → 3D-QSAR illusions(2004)133 cited
- → QSAR: dead or alive?(2008)132 cited
- → The hypothetical active site lattice. An approach to modelling active sites from data on inhibitor molecules(1988)113 cited
- → Selective Itk Inhibitors Block T-Cell Activation and Murine Lung Inflammation(2004)112 cited
- → Design and Synthesis of N-[(4-Methoxyphenoxy)carbonyl]-N-[[4-[2-(5- methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]methyl]glycine [Muraglitazar/BMS-298585], a Novel Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist with Efficacious Glucose and Lipid-Lowering Activities(2004)108 cited
- → Discovery of 2-amino-heteroaryl-benzothiazole-6-anilides as potent p56lck inhibitors(2003)106 cited