Lisa Sherman
Amgen (United States)(US)
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Synthesis and biological activity, Protein Kinase Regulation and GTPase Signaling, Computational Drug Discovery Methods, Cancer Mechanisms and Therapy
Most-Cited Works
- → Discovery of Highly Selective and Potent p38 Inhibitors Based on a Phthalazine Scaffold(2008)58 cited
- → Discovery and Evaluation of 7-Alkyl-1,5-bis-aryl-pyrazolopyridinones as Highly Potent, Selective, and Orally Efficacious Inhibitors of p38α Mitogen-Activated Protein Kinase⊥⊥ Atomic coordinates and structure factors for crystal structure of compound3dwith p38α can be accessed using PDB code 3LHJ.(2010)30 cited
- → 3-Amino-7-phthalazinylbenzoisoxazoles as a Novel Class of Potent, Selective, and Orally Available Inhibitors of p38α Mitogen-Activated Protein Kinase(2008)26 cited
- → Part 1: Structure–Activity Relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38α mitogen-activated protein kinase(2009)20 cited
- → Part 2: Structure–activity relationship (SAR) investigations of fused pyrazoles as potent, selective and orally available inhibitors of p38α mitogen-activated protein kinase(2010)18 cited
- → Discovery of Pyridazinopyridinones as Potent and Selective p38 Mitogen-Activated Protein Kinase Inhibitors(2010)17 cited
- → Predictability of Peripheral Lymphocyte Reduction of Novel S1P1 Agonists by In Vitro GPCR Signaling Profile(2013)5 cited
- → Identification of triazolopyridazinones as potent p38α inhibitors(2011)3 cited