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Magid Abou‐Gharbia | doi.page

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Magid Abou‐Gharbia

Temple University(US)

Publications by Year

Research Areas

Epigenetics and DNA Methylation, Uterine Myomas and Treatments, Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research, Synthesis and Biological Evaluation

Most-Cited Works

→ Desvenlafaxine Succinate: A New Serotonin and Norepinephrine Reuptake Inhibitor(2006)377 cited
→ Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer(2018)224 cited
→ Resistance to BET Bromodomain Inhibitors Is Mediated by Kinome Reprogramming in Ovarian Cancer(2016)200 cited
→ Tiplaxtinin, a Novel, Orally Efficacious Inhibitor of Plasminogen Activator Inhibitor-1: Design, Synthesis, and Preclinical Characterization(2004)166 cited
→ Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein γ-Secretase for the Treatment of Alzheimer’s Disease(2009)157 cited
→ Enhanced clearance of Aβ in brain by sustaining the plasmin proteolysis cascade(2008)140 cited

→ Design, Synthesis, and Preclinical Characterization of Novel, Highly Selective Indole Estrogens(2001)

137 cited

→ Lecozotan (SRA-333): A Selective Serotonin 1A Receptor Antagonist That Enhances the Stimulated Release of Glutamate and Acetylcholine in the Hippocampus and Possesses Cognitive-Enhancing Properties(2005)130 cited

→ Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities(2007)111 cited

→ Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease(2008)109 cited