Oscar Vadas
University of Geneva(CH)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Toxoplasma gondii Research Studies, Protein Kinase Regulation and GTPase Signaling, Chronic Lymphocytic Leukemia Research, Influenza Virus Research Studies
Most-Cited Works
- → Phosphoinositide 3-Kinase δ Gene Mutation Predisposes to Respiratory Infection and Airway Damage(2013)612 cited
- → Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α ( PIK3CA )(2012)312 cited
- → Structural Basis for Activation and Inhibition of Class I Phosphoinositide 3-Kinases(2011)295 cited
- → Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism(2011)202 cited
- → G Protein–Coupled Receptor–Mediated Activation of p110β by Gβγ Is Required for Cellular Transformation and Invasiveness(2012)147 cited
- → Molecular determinants of PI3Kγ-mediated activation downstream of G-protein–coupled receptors (GPCRs)(2013)137 cited
- → Conformational disruption of PI3Kδ regulation by immunodeficiency mutations in PIK3CD and PIK3R1(2017)127 cited
- → Dynamics of the Phosphoinositide 3-Kinase p110δ Interaction with p85α and Membranes Reveals Aspects of Regulation Distinct from p110α(2011)107 cited
- → Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma(2020)100 cited
- → PI(3,4)P2-mediated cytokinetic abscission prevents early senescence and cataract formation(2021)70 cited