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Sidney M. Hecht | doi.page

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Sidney M. Hecht

Publications by Year

Research Areas

DNA and Nucleic Acid Chemistry, RNA and protein synthesis mechanisms, Cancer therapeutics and mechanisms, Chemical Synthesis and Analysis, RNA modifications and cancer

Most-Cited Works

→ Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.(1985)2,338 cited
→ On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex(1989)552 cited
→ Bleomycin: New Perspectives on the Mechanism of Action(1999)547 cited
→ Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity(1991)516 cited
→ Camptothecin: current perspectives(2004)437 cited
→ gamma Ray induced deoxyribonucleic acid strand breaks. 3' Glycolate termini.(1983)322 cited

→ The chemistry of activated bleomycin(1986)

287 cited

→ The Dynamic Character of the BCL2 Promoter i-Motif Provides a Mechanism for Modulation of Gene Expression by Compounds That Bind Selectively to the Alternative DNA Hairpin Structure(2014)279 cited

→ Identification of the First Specific Inhibitor of p90 Ribosomal S6 Kinase (RSK) Reveals an Unexpected Role for RSK in Cancer Cell Proliferation(2005)276 cited

→ Eukaryotic mRNA cap binding protein: purification by affinity chromatography on sepharose-coupled m7GDP.(1979)263 cited