Denis Guédin
Servier (France)(FR)Institut du Cerveau(FR)
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Nitric Oxide and Endothelin Effects, Ion channel regulation and function, Genetic Neurodegenerative Diseases, Neuroscience and Neuropharmacology Research
Most-Cited Works
- → Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system(2009)685 cited
- → Why are circulating concentrations of endothelin-1 so low?(1994)114 cited
- → High Affinity Binding of Pyrethroids to the α Subunit of Brain Sodium Channels(1997)80 cited
- → Direct Block of Voltage-Sensitive Sodium Channels by Genistein, A Tyrosine Kinase Inhibitor(1997)78 cited
- → Discovery of Diarylhydantoins as New Selective Androgen Receptor Modulators(2012)75 cited
- → Systematic identification of mutations that constitutively activate the angiotensin II type 1A receptor by screening a randomly mutated cDNA library with an original pharmacological bioassay(2000)68 cited
- → The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells(2019)55 cited
- → Identification of a 4-(Hydroxymethyl)diarylhydantoin as a Selective Androgen Receptor Modulator(2012)51 cited
- → Neurotoxin binding and allosteric modulation at receptor sites 2 and 5 on purified and reconstituted rat brain sodium channels(1993)51 cited
- → Parkin maintains mitochondrial levels of the protective Parkinson’s disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10(2015)40 cited