Arthur Gomtsyan

Publications by Year

Research Areas

Ion Channels and Receptors, Pain Mechanisms and Treatments, Asymmetric Synthesis and Catalysis, Quinazolinone synthesis and applications, Herbal Medicine Research Studies

Most-Cited Works

• → Heterocycles in drugs and drug discovery(2012)585 cited
• → TRPV1 Receptors in the CNS Play a Key Role in Broad-Spectrum Analgesia of TRPV1 Antagonists(2006)311 cited
• → A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel Transient Receptor Potential Type V1 Receptor Antagonist, Relieves Pathophysiological Pain Associated with Inflammation and Tissue Injury in Rats(2005)254 cited
• → Novel Transient Receptor Potential Vanilloid 1 Receptor Antagonists for the Treatment of Pain: Structure−Activity Relationships for Ureas with Quinoline, Isoquinoline, Quinazoline, Phthalazine, Quinoxaline, and Cinnoline Moieties(2005)163 cited
• → Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia(2009)145 cited
• → A-425619 [1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a Novel and Selective Transient Receptor Potential Type V1 Receptor Antagonist, Blocks Channel Activation by Vanilloids, Heat, and Acid(2005)110 cited
• → Molecular Recognition and Self-Assembly by Weak Hydrogen Bonding: Unprecedented Supramolecular Helicate Structures from Diamine/Diol Motifs(1994)107 cited
• → Asymmetric synthesis of enantiomerically pure and diversely functionalized cyclopropanes.(1995)105 cited
• → ABT-702 (4-Amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3-yl)pyrido[2,3-d]pyrimidine), a Novel Orally Effective Adenosine Kinase Inhibitor with Analgesic and Anti-Inflammatory Properties. II. In Vivo Characterization in the Rat(2000)104 cited
• → TRPV1 antagonists that cause hypothermia, instead of hyperthermia, in rodents: Compounds’ pharmacological profiles, in vivo targets, thermoeffectors recruited and implications for drug development(2018)87 cited