Alex G. Waterson
Vanderbilt University(US)Institute of Pharmacology(CZ)
Publications by Year
Research Areas
Protein Kinase Regulation and GTPase Signaling, Click Chemistry and Applications, DNA Repair Mechanisms, ATP Synthase and ATPases Research, Receptor Mechanisms and Signaling
Most-Cited Works
- → Discovery of Small Molecules that Bind to K‐Ras and Inhibit Sos‐Mediated Activation(2012)495 cited
- → Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α(2010)479 cited
- → Drugging an undruggable pocket on KRAS(2019)420 cited
- → Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors(2013)254 cited
- → Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange(2014)187 cited
- → Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)(2017)149 cited
- → Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy