Karl H. Clodfelter
Forma Therapeutics (United States)(US)
Publications by Year
Research Areas
Biochemical and Molecular Research, Sirtuins and Resveratrol in Medicine, Protein Structure and Dynamics, Growth Hormone and Insulin-like Growth Factors, Computational Drug Discovery Methods
Most-Cited Works
- → Sex-Dependent Liver Gene Expression Is Extensive and Largely Dependent upon Signal Transducer and Activator of Transcription 5b (STAT5b): STAT5b-Dependent Activation of Male Genes and Repression of Female Genes Revealed by Microarray Analysis(2006)240 cited
- → Sexual Dimorphism of Rat Liver Gene Expression: Regulatory Role of Growth Hormone Revealed by Deoxyribonucleic Acid Microarray Analysis(2003)137 cited
- → Optimal Clustering for Detecting Near-Native Conformations in Protein Docking(2005)132 cited
- → Structure-Based Discovery of Novel Amide-Containing Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors(2013)80 cited
- → Identification of Substrate Binding Sites in Enzymes by Computational Solvent Mapping(2003)74 cited
- → Structure-Based Identification of Ureas as Novel Nicotinamide Phosphoribosyltransferase (Nampt) Inhibitors(2013)68 cited
- → Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis(2007)64 cited
- → Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)(2013)41 cited
- → Discovery of potent and efficacious urea-containing nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with reduced CYP2C9 inhibition properties(2013)41 cited
- → Computational Solvent Mapping Reveals the Importance of Local Conformational Changes for Broad Substrate Specificity in Mammalian Cytochromes P450(2006)36 cited