Iain T. Collie
AstraZeneca (Germany)(DE)
Publications by Year
Research Areas
Trypanosoma species research and implications, Research on Leishmaniasis Studies, Biochemical and Molecular Research, Synthesis and Biological Evaluation, Computational Drug Discovery Methods
Most-Cited Works
- → One Scaffold, Three Binding Modes: Novel and Selective Pteridine Reductase 1 Inhibitors Derived from Fragment Hits Discovered by Virtual Screening(2009)106 cited
- → The First Potent and Selective Inhibitors of the Glycine Transporter Type 2(2001)99 cited
- → HTS and hit finding in academia – from chemical genomics to drug discovery(2009)82 cited
- → Molecular cloning and functional expression of the human glycine transporter GlyT2 and chromosomal localisation of the gene in the human genome1(1998)73 cited
- → A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N -Myristoyltransferase Inhibitors(2018)53 cited
- → Identification of Inhibitors of the Leishmania cdc2‐Related Protein Kinase CRK3(2011)47 cited
- → Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1(2010)45 cited
- → Fragment-Based Design of a Potent MAT2a Inhibitor and in Vivo Evaluation in an MTAP Null Xenograft Model(2021)33 cited
- → Discovery of Indoline-2-carboxamide Derivatives as a New Class of Brain-Penetrant Inhibitors ofTrypanosoma brucei(2015)27 cited
- → A Novel Allosteric Inhibitor of the Uridine Diphosphate N-Acetylglucosamine Pyrophosphorylase from Trypanosoma brucei(2013)26 cited