Scott C. Mayer
Tulane University(US)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Cholinesterase and Neurodegenerative Diseases, Synthetic Organic Chemistry Methods, Alzheimer's disease research and treatments, Computational Drug Discovery Methods
Most-Cited Works
- → Begacestat (GSI-953): A Novel, Selective Thiophene Sulfonamide Inhibitor of Amyloid Precursor Protein γ-Secretase for the Treatment of Alzheimer’s Disease(2009)157 cited
- → Discovery of Begacestat, a Notch-1-Sparing γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease(2008)109 cited
- → Pharmacological comparison of muscarinic ligands: Historical versus more recent muscarinic M1-preferring receptor agonists(2009)99 cited
- → Synthesis of New Didemnin B Analogs for Investigations of Structure/Biological Activity Relationships(1994)67 cited
- → Lead identification to generate isoquinolinedione inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment(2008)67 cited
- → Comparative Study of Selected Coupling Reagents in Dipeptide Synthesis(1993)52 cited
- → Lead identification to generate 3-cyanoquinoline inhibitors of insulin-like growth factor receptor (IGF-1R) for potential use in cancer treatment(2008)42 cited
- → Direct Inhibition ofIhby Analgesic Loperamide in Rat DRG Neurons(2007)38 cited
- → Neutralization of Plasminogen Activator Inhibitor I (PAI-1) by the Synthetic Antagonist PAI-749 via a Dual Mechanism of Action(2007)28 cited
- → Molecular-modeling based design, synthesis, and activity of substituted piperidines as γ-secretase inhibitors(2005)20 cited