Brett J Winborn
St. Jude Children's Research Hospital(US)
Publications by Year
Research Areas
Genetic Neurodegenerative Diseases, Mitochondrial Function and Pathology, Ubiquitin and proteasome pathways, Autophagy in Disease and Therapy, Amyotrophic Lateral Sclerosis Research
Most-Cited Works
- → Axonal Transport of TDP-43 mRNA Granules Is Impaired by ALS-Causing Mutations(2014)639 cited
- → Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis(2014)441 cited
- → The Deubiquitinating Enzyme Ataxin-3, a Polyglutamine Disease Protein, Edits Lys63 Linkages in Mixed Linkage Ubiquitin Chains(2008)257 cited
- → VCP Is Essential for Mitochondrial Quality Control by PINK1/Parkin and this Function Is Impaired by VCP Mutations(2013)237 cited
- → Ubiquitination directly enhances activity of the deubiquitinating enzyme ataxin‐3(2009)170 cited
- → Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1(2015)75 cited
- → Cellular Turnover of the Polyglutamine Disease Protein Ataxin-3 Is Regulated by Its Catalytic Activity(2007)51 cited
- → Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy(2018)44 cited
- → MAP4K3 inhibits Sirtuin-1 to repress the LKB1–AMPK pathway to promote amino acid-dependent activation of the mTORC1 complex(2023)4 cited