Keith W. Woods
University of North Carolina at Chapel Hill(US)
Publications by Year
Research Areas
PI3K/AKT/mTOR signaling in cancer, Synthesis and biological activity, Quinazolinone synthesis and applications, Protein Kinase Regulation and GTPase Signaling, Synthesis and Catalytic Reactions
Most-Cited Works
- → Potent, Orally Active Heterocycle-Based Combretastatin A-4 Analogues: Synthesis, Structure−Activity Relationship, Pharmacokinetics, and In Vivo Antitumor Activity Evaluation(2002)420 cited
- → Potent and selective inhibitors of Akt kinases slow the progress of tumors in vivo(2005)244 cited
- → Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition(2007)169 cited
- → Synthesis and Biological Evaluation of 2-Indolyloxazolines as a New Class of Tubulin Polymerization Inhibitors. Discovery of A-289099 as an Orally Active Antitumor Agent(2002)123 cited
- → Pharmacological and Functional Comparison of the Polo-like Kinase Family: Insight into Inhibitor and Substrate Specificity(2007)115 cited
- → Synthesis and SAR of novel tricyclic quinoxalinone inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1)(2009)106 cited
- → Synthesis and SAR of indazole-pyridine based protein kinase B/Akt inhibitors(2006)81 cited
- → Benzimidazolones and indoles as non-thiol farnesyltransferase inhibitors based on tipifarnib scaffold: synthesis and activity(2005)73 cited
- → Optimal Classes of Chemotherapeutic Agents Sensitized by Specific Small-Molecule Inhibitors of Akt In Vitro and In Vivo(2005)64 cited
- → Syntheses of Potent, Selective, and Orally Bioavailable Indazole-Pyridine Series of Protein Kinase B/Akt Inhibitors with Reduced Hypotension(2007)62 cited