Larry W. Hertel
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Biochemical and Molecular Research, DNA Repair Mechanisms, Asymmetric Synthesis and Catalysis, DNA and Nucleic Acid Chemistry
Most-Cited Works
- Action of 2',2'-difluorodeoxycytidine on DNA synthesis.(1991)
- Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine).(1990)
- Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine.(1988)
- → Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.(1990)406 cited
- → Synthesis of 2-deoxy-2,2-difluoro-D-ribose and 2-deoxy-2,2'-difluoro-D-ribofuranosyl nucleosides(1988)362 cited
- Cellular elimination of 2',2'-difluorodeoxycytidine 5'-triphosphate: a mechanism of self-potentiation.(1992)
- → Radiosensitization of pancreatic cancer cells by 2′,2′-difluoro-2′-deoxycytidine(1996)311 cited
- Metabolism of 2',2'-difluoro-2'-deoxycytidine and radiation sensitization of human colon carcinoma cells.(1994)
- → Nucleotide specificity of human deoxycytidine kinase.(1992)123 cited
- → Comparison of the antitumor activity of gemcitabine and ara-C in a panel of human breast, colon, lung and pancreatic xenograft models(1996)80 cited