Ana Isabel de Lucas
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research, Chemical Synthesis and Analysis, Organic and Molecular Conductors Research, Pharmacological Receptor Mechanisms and Effects
Most-Cited Works
- → Discovery of 3-Cyclopropylmethyl-7-(4-phenylpiperidin-1-yl)-8-trifluoromethyl[1,2,4]triazolo[4,3-a]pyridine (JNJ-42153605): A Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor(2012)85 cited
- → Scaffold hopping from pyridones to imidazo[1,2-a]pyridines. New positive allosteric modulators of metabotropic glutamate 2 receptor(2009)73 cited
- → The first tetrathiafulvalene derivatives exhibiting second-order NLO properties(1998)70 cited
- → Imidazo[1,2-a]pyridines: Orally Active Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor(2012)60 cited
- → Discovery of 1-Butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1 H )-pyridone (JNJ-40411813): A Novel Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor(2014)56 cited
- → Discovery of a New Series of Centrally Active Tricyclic Isoxazoles Combining Serotonin (5-HT) Reuptake Inhibition with α2-Adrenoceptor Blocking Activity(2004)49 cited
- → New TTF-based donor-acceptor molecules linked by flexible ethylenic spacers(1997)44 cited
- → Discovery of 8-Trifluoromethyl-3-cyclopropylmethyl-7-[(4-(2,4-difluorophenyl)-1-piperazinyl)methyl]-1,2,4-triazolo[4,3-a]pyridine (JNJ-46356479), a Selective and Orally Bioavailable mGlu2 Receptor Positive Allosteric Modulator (PAM)(2016)37 cited
- → Discovery of 1,4-Disubstituted 3-Cyano-2-pyridones: A New Class of Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor(2012)34 cited
- → Evaluation of a Series of β-Secretase 1 Inhibitors Containing Novel Heteroaryl-Fused-Piperazine Amidine Warheads(2019)33 cited