Sascha Weggen
Heinrich Heine University Düsseldorf(DE)
Publications by Year
Research Areas
Alzheimer's disease research and treatments, Cholinesterase and Neurodegenerative Diseases, Computational Drug Discovery Methods, Drug Transport and Resistance Mechanisms, Cellular transport and secretion
Most-Cited Works
- → A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity(2001)1,380 cited
- → NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo(2003)618 cited
- → Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier(2015)442 cited
- → Evidence That Nonsteroidal Anti-inflammatory Drugs Decrease Amyloid β42 Production by Direct Modulation of γ-Secretase Activity(2003)287 cited
- → Diverse compounds mimic Alzheimer disease–causing mutations by augmenting Aβ42 production(2005)280 cited
- → DOGS: Reaction-Driven de novo Design of Bioactive Compounds(2012)263 cited
- → FE65 Constitutes the Functional Link between the Low-Density Lipoprotein Receptor-Related Protein and the Amyloid Precursor Protein