Lea Sefer
University of Oxford(GB)
Publications by Year
Research Areas
Hedgehog Signaling Pathway Studies, Genomics and Chromatin Dynamics, Epigenetics and DNA Methylation, Alzheimer's disease research and treatments, Bacterial biofilms and quorum sensing
Most-Cited Works
- → The Bacterial Curli System Possesses a Potent and Selective Inhibitor of Amyloid Formation(2015)205 cited
- → Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones(2016)66 cited
- → Structure, mechanism, and inhibition of Hedgehog acyltransferase(2021)54 cited
- → Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes(2019)36 cited
- → NMR insights into the pre-amyloid ensemble and secretion targeting of the curli subunit CsgA(2020)20 cited
- → Design, Synthesis, and Evaluation of Inhibitors of Hedgehog Acyltransferase(2024)5 cited
- → Structure and Mechanism of Hedgehog Acyl Transferase(2021)3 cited
- → Photochemical probe identification of the small-molecule binding site in a mammalian membrane-bound O -acyltransferase(2020)1 cited
- → Photochemical Probe Identification of a Small‐Molecule Inhibitor Binding Site in Hedgehog Acyltransferase (HHAT)**(2021)1 cited
- Bacterial expression of interferon alpha with new approaches to its PEGylation(2011)