Randall W. Hungate
Publications by Year
Research Areas
Chemical Synthesis and Analysis, HIV/AIDS drug development and treatment, Coagulation, Bradykinin, Polyphosphates, and Angioedema, Synthetic Organic Chemistry Methods, Hormonal Regulation and Hypertension
Most-Cited Works
- → Discovery and Optimization of Chromenotriazolopyrimidines as Potent Inhibitors of the Mouse Double Minute 2−Tumor Protein 53 Protein−Protein Interaction(2009)147 cited
- → The total synthesis of avermectin A1a(1989)138 cited
- → Vascular Endothelial Growth Factor Receptor KDR Tyrosine Kinase Activity Is Increased by Autophosphorylation of Two Activation Loop Tyrosine Residues(1999)133 cited
- → Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents(2006)125 cited
- → Synthesis and Initial SAR Studies of 3,6-Disubstituted Pyrazolo[1,5-a]pyrimidines: A New Class of KDR Kinase Inhibitors(2002)112 cited
- → The total synthesis of the aglycon of avermectin A1a(1987)103 cited
- → Design, Synthesis, and Biological Evaluation of Potent c-Met Inhibitors(2008)90 cited
- → Optimization of a pyrazolo[1,5-a]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharmacokinetics(2002)87 cited
- → Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3Kδ Inhibitors for Inflammation and Autoimmune Disease(2014)85 cited
- → Discovery of a Potent, Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Clinical Study: Identification of (S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221)(2010)80 cited