Karen E. Parrish
AbbVie (United States)(US)
Publications by Year
Research Areas
Glioma Diagnosis and Treatment, PARP inhibition in cancer therapy, Drug Transport and Resistance Mechanisms, Cancer Mechanisms and Therapy, DNA Repair Mechanisms
Most-Cited Works
- → Strategies to improve delivery of anticancer drugs across the blood–brain barrier to treat glioblastoma(2015)274 cited
- → Efflux Transporters at the Blood-Brain Barrier Limit Delivery and Efficacy of Cyclin-Dependent Kinase 4/6 Inhibitor Palbociclib (PD-0332991) in an Orthotopic Brain Tumor Model(2015)96 cited
- → Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System(2015)87 cited
- → Barriers to Effective Drug Treatment for Brain Metastases: A Multifactorial Problem in the Delivery of Precision Medicine(2018)79 cited
- → Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor(2021)75 cited
- → Restricted Delivery of Talazoparib Across the Blood–Brain Barrier Limits the Sensitizing Effects of PARP Inhibition on Temozolomide Therapy in Glioblastoma(2017)72 cited
- → ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model(2016)60 cited
- → Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1(2021)51 cited
- → Efficacy of the MDM2 Inhibitor SAR405838 in Glioblastoma Is Limited by Poor Distribution Across the Blood–Brain Barrier(2018)40 cited
- → Pharmacokinetic Assessment of Cooperative Efflux of the Multitargeted Kinase Inhibitor Ponatinib Across the Blood-Brain Barrier(2018)33 cited