Sean R. Downing
Publications by Year
Research Areas
Cancer Genomics and Diagnostics, Bladder and Urothelial Cancer Treatments, Cancer Cells and Metastasis, Prostate Cancer Treatment and Research, Urinary and Genital Oncology Studies
Most-Cited Works
- → Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing(2013)2,153 cited
- → Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies(2012)862 cited
- → Targeted Next-generation Sequencing of Advanced Prostate Cancer Identifies Potential Therapeutic Targets and Disease Heterogeneity(2012)454 cited
- → Advanced urothelial carcinoma: next-generation sequencing reveals diverse genomic alterations and targets of therapy(2013)147 cited
- → A High Frequency of Activating Extracellular Domain ERBB2 ( HER2 ) Mutation in Micropapillary Urothelial Carcinoma(2013)136 cited
- → Relapsed Classic E-Cadherin ( CDH1 )–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of HER2 ( ERBB2 ) Gene Mutations(2013)133 cited
- → Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer(2012)131 cited
- → Comprehensive Genomic Profiling of Relapsed and Metastatic Adenoid Cystic Carcinomas by Next-generation Sequencing Reveals Potential New Routes to Targeted Therapies(2014)62 cited
- → Response of an ERBB2-Mutated Inflammatory Breast Carcinoma to Human Epidermal Growth Factor Receptor 2–Targeted Therapy(2014)47 cited
- → Combination antiangiogenic therapy in advanced breast cancer: a phase 1 trial of vandetanib, a VEGFR inhibitor, and metronomic chemotherapy, with correlative platelet proteomics(2012)44 cited