Emmanuel H. Demont
Age UK(GB)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Multiple Myeloma Research and Treatments, Ubiquitin and proteasome pathways, Asymmetric Synthesis and Catalysis, Synthetic Organic Chemistry Methods
Most-Cited Works
- → Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation(2020)416 cited
- → Oral administration of a potent and selective non‐peptidic BACE‐1 inhibitor decreases β‐cleavage of amyloid precursor protein and amyloid‐β production in vivo(2006)198 cited
- → The Discovery of I-BET726 (GSK1324726A), a Potent Tetrahydroquinoline ApoA1 Up-Regulator and Selective BET Bromodomain Inhibitor(2014)187 cited
- → Discovery of Tetrahydroquinoxalines as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the Second Bromodomain(2018)118 cited
- → 1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain(2014)89 cited
- → GSK789: A Selective Inhibitor of the First Bromodomains (BD1) of the Bromo and Extra Terminal Domain (BET) Proteins(2020)84 cited
- → Structure-Based Optimization of Naphthyridones into Potent ATAD2 Bromodomain Inhibitors(2015)83 cited
- → Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors(2015)79 cited
- → A Chemical Probe for the ATAD2 Bromodomain(2016)75 cited
- → Domain-selective targeting of BET proteins in cancer and immunological diseases(2020)74 cited