Jeremy S. Disch
University of Stuttgart(DE)BVI (United States)(US)
Publications by Year
Research Areas
Crystallization and Solubility Studies, X-ray Diffraction in Crystallography, Sirtuins and Resveratrol in Medicine, Biochemical effects in animals, Protein Degradation and Inhibitors
Most-Cited Works
- → Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes(2007)1,679 cited
- → Crystallographic structure of a small molecule SIRT1 activator-enzyme complex(2015)198 cited
- → Discovery of Thieno[3,2-d]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3(2013)191 cited
- → Discovery of Imidazo[1,2- b ]thiazole Derivatives as Novel SIRT1 Activators(2009)117 cited
- → Discovery of oxazolo[4,5-b]pyridines and related heterocyclic analogs as novel SIRT1 activators(2008)90 cited
- → Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening(2021)70 cited
- → Discovery of Nanomolar DCAF1 Small Molecule Ligands(2023)59 cited
- → Reactions at the azomethine CN bonds in the nickel(ii) and copper(ii) complexes of pyridine-containing Schiff-base macrocyclic ligands(2003)36 cited
- → Generating Selective Leads for Mer Kinase Inhibitors—Example of a Comprehensive Lead-Generation Strategy(2021)26 cited
- → Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators(2013)25 cited