Hans Gaus
Ionis Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
DNA and Nucleic Acid Chemistry, Advanced biosensing and bioanalysis techniques, RNA Interference and Gene Delivery, RNA and protein synthesis mechanisms, Mass Spectrometry Techniques and Applications
Most-Cited Works
- → Targeted delivery of antisense oligonucleotides to hepatocytes using triantennaryN-acetyl galactosamine improves potency 10-fold in mice(2014)580 cited
- → Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates(2014)269 cited
- → Single-Stranded siRNAs Activate RNAi in Animals(2012)255 cited
- → Cross-Species Pharmacokinetic Comparison from Mouse to Man of a Second-Generation Antisense Oligonucleotide, ISIS 301012, Targeting Human Apolipoprotein B-100(2006)237 cited
- → Synthesis and Biophysical Evaluation of 2′,4′-Constrained 2′O-Methoxyethyl and 2′,4′-Constrained 2′O-Ethyl Nucleic Acid Analogues(2010)209 cited
- → Measurement of Macromolecular Binding Using Electrospray Mass Spectrometry. Determination of Dissociation Constants for Oligonucleotide: Serum Albumin Complexes(1995)153 cited