Laura Aldegheri
Aptuit (Italy)(IT)
Publications by Year
Research Areas
Neuroscience and Neuropharmacology Research, Ion channel regulation and function, Receptor Mechanisms and Signaling, Pharmacological Receptor Mechanisms and Effects, Cardiac electrophysiology and arrhythmias
Most-Cited Works
- → Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS(2002)242 cited
- → Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators(2010)66 cited
- → A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons(2015)63 cited
- → Pharmacological properties of rat α7 nicotinic receptors expressed in native and recombinant cell systems(2002)49 cited
- → Discovery ofN-[(2S)-5-(6-Fluoro-3-pyridinyl)-2,3-dihydro-1H-inden-2-yl]-2-propanesulfonamide, a Novel Clinical AMPA Receptor Positive Modulator(2010)47 cited
- → The antidepressant fluoxetine blocks the human small conductance calcium-activated potassium channels SK1, SK2 and SK3(2003)39 cited
- → Characterization of three diaminopyrimidines as potent and selective antagonists of P2X3 and P2X2/3 receptors within vivoefficacy in a pain model(2011)30 cited
- → High Throughput Scintillation Proximity Assay for the Identification of FKBP-12 Ligands(1999)21 cited
- → From High-Throughput Screening to Target Validation: Benzo[d]isothiazoles as Potent and Selective Agonists of Human Transient Receptor Potential Cation Channel Subfamily M Member 5 Possessing In Vivo Gastrointestinal Prokinetic Activity in Rodents(2021)16 cited
- → Pharmacological characterisation of MDI-222, a novel AMPA receptor positive allosteric modulator with an improved safety profile(2019)16 cited