Laura A. Lopez-Garcia
Publications by Year
Research Areas
Protein Kinase Regulation and GTPase Signaling, FOXO transcription factor regulation, PI3K/AKT/mTOR signaling in cancer, RNA modifications and cancer, Sarcoma Diagnosis and Treatment
Most-Cited Works
- → Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1(2009)143 cited
- → Allosteric activation of the protein kinase PDK1 with low molecular weight compounds(2006)110 cited
- → Substrate-Selective Inhibition of Protein Kinase PDK1 by Small Compounds that Bind to the PIF-Pocket Allosteric Docking Site(2012)82 cited
- → 3,5-Diphenylpent-2-enoic Acids as Allosteric Activators of the Protein Kinase PDK1: Structure−Activity Relationships and Thermodynamic Characterization of Binding as Paradigms for PIF-Binding Pocket-Targeting Compounds†PDB code of 2Z with PDK1: 3HRF.(2009)77 cited
- → Allosteric Regulation of Protein Kinase PKCζ by the N-Terminal C1 Domain and Small Compounds to the PIF-Pocket(2011)65 cited
- → PLK1 Phosphorylates PAX3-FOXO1, the Inhibition of Which Triggers Regression of Alveolar Rhabdomyosarcoma(2014)50 cited
- → 2-(3-Oxo-1,3-diphenylpropyl)malonic Acids as Potent Allosteric Ligands of the PIF Pocket of Phosphoinositide-Dependent Kinase-1: Development and Prodrug Concept(2012)42 cited
- → USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth(2019)39 cited
- → Regulation of the Interaction between Protein Kinase C-related Protein Kinase 2 (PRK2) and Its Upstream Kinase, 3-Phosphoinositide-dependent Protein Kinase 1 (PDK1)(2009)34 cited
- → 4-Benzimidazolyl-3-Phenylbutanoic Acids As Novel Pif-Pocket-Targeting Allosteric Inhibitors of Protein Kinase PKCζ(2011)34 cited