Simon Xi
Io Therapeutics (United States)(US)
Publications by Year
Research Areas
Genetic Associations and Epidemiology, Bipolar Disorder and Treatment, Genetics and Neurodevelopmental Disorders, Receptor Mechanisms and Signaling, Genomic variations and chromosomal abnormalities
Most-Cited Works
- → ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia(2012)2,202 cited
- → Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue(2020)80 cited
- → Discovery of Small-Molecule CD33 Pre-mRNA Splicing Modulators(2022)16 cited
- → The Design, Synthesis and Potential Utility of Fluorescence Probes that Target DFG‐out Conformation of p38α for High Throughput Screening Binding Assay(2009)11 cited
- → ABACUS: A flexible UMI counter that leverages intronic reads for single-nucleus RNAseq analysis(2020)7 cited
- → Effect of RGT-61159 on inhibition of oncogene c-MYB synthesis and tumor growth inhibition in a broad range of ACC PDX models, at well tolerated doses in rodents and non-human primates.(2024)5 cited
- → Genome‐wide tissue transcriptome profiling and ligand screening identify seven striatum‐specific human orphan GPCRs(2017)2 cited
- → I007 Developing RNA-targeting oral small molecules to treat repeat expansion disorders(2024)
- → High throughput screening at novel striatum orphan GPCRs identified by human transcriptomic profiling(2019)
- → RGT-61159, Best-in-Class Small Molecule Inhibitor of MYB Via Selective RNA Splicing Alteration, Showed Robust Anti-Tumor Activity across AML Tumor Models Harboring Common Genetic Lesions(2024)