Karl Welzenbach
Novartis (Switzerland)(CH)
Publications by Year
Research Areas
Cell Adhesion Molecules Research, Monoclonal and Polyclonal Antibodies Research, Immune Response and Inflammation, Protein Kinase Regulation and GTPase Signaling, Immunotherapy and Immune Responses
Most-Cited Works
- → Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site(2001)1,038 cited
- → Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain 1 1Edited by F. E. Cohen(1999)256 cited
- → ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157(2017)181 cited
- → The Potent Protein Kinase C-Selective Inhibitor AEB071 (Sotrastaurin) Represents a New Class of Immunosuppressive Agents Affecting Early T-Cell Activation(2009)159 cited
- → Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer(2005)150 cited
- → Small Molecule Inhibitors Induce Conformational Changes in the I Domain and the I-like Domain of Lymphocyte Function-associated Antigen-1(2002)80 cited
- → Improved Lymphocyte Function-associated Antigen-1 (LFA-1) Inhibition by Statin Derivatives(2004)68 cited
- → CD47 fusion protein targets CD172a+ cells in Crohn’s disease and dampens the production of IL-1β and TNF(2013)55 cited
- → 1,4-Diazepane-2-ones as novel inhibitors of LFA-1(2003)50 cited
- → 1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1(2004)44 cited