Ruth Lehr
Publications by Year
Research Areas
Protein Kinase Regulation and GTPase Signaling, Cell death mechanisms and regulation, Immune Response and Inflammation, Cancer-related Molecular Pathways, Chemical Synthesis and Analysis
Most-Cited Works
- → Inhibition of Transforming Growth Factor (TGF)-β1–Induced Extracellular Matrix with a Novel Inhibitor of the TGF-β Type I Receptor Kinase Activity: SB-431542(2002)647 cited
- → Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases(2017)466 cited
- → Identification and Initial Characterization of Four Novel Members of the Interleukin-1 Family(2000)361 cited
- → Identification of Novel Inhibitors of the Transforming Growth Factor β1 (TGF-β1) Type 1 Receptor (ALK5)(2002)309 cited
- → DNA-Encoded Library Screening Identifies Benzo[b][1,4]oxazepin-4-ones as Highly Potent and Monoselective Receptor Interacting Protein 1 Kinase Inhibitors(2016)269 cited
- → INTERLEUKIN-1F7B (IL-1H4/IL-1F7) IS PROCESSED BY CASPASE-1 AND MATURE IL-1F7B BINDS TO THE IL-18 RECEPTOR BUT DOES NOT INDUCE IFN-γ PRODUCTION(2002)255 cited
- → Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis(2013)135 cited
- → Effects of oncogenic p110α subunit mutations on the lipid kinase activity of phosphoinositide 3-kinase(2007)118 cited
- → ATP-competitive inhibitors of the mitotic kinesin KSP that function via an allosteric mechanism(2007)108 cited
- → The structure of ribonuclease P protein from Staphylococcus aureus reveals a unique binding site for single-stranded RNA(2000)103 cited