Judith S. Sebolt–Leopold
University of Michigan–Ann Arbor(US)
Publications by Year
Research Areas
Melanoma and MAPK Pathways, Colorectal Cancer Treatments and Studies, Pancreatic and Hepatic Oncology Research, Advanced Breast Cancer Therapies, PI3K/AKT/mTOR signaling in cancer
Most-Cited Works
- → BRAF mutation predicts sensitivity to MEK inhibition(2005)1,325 cited
- → Targeting the mitogen-activated protein kinase cascade to treat cancer(2004)1,109 cited
- → Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo(1999)967 cited
- → Multicenter Phase II Study of the Oral MEK Inhibitor, CI-1040, in Patients With Advanced Non-Small-Cell Lung, Breast, Colon, and Pancreatic Cancer(2004)637 cited
- → Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition(2004)614 cited
- → Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon(2008)595 cited
- → Phase I and Pharmacodynamic Study of the Oral MEK Inhibitor CI-1040 in Patients With Advanced Malignancies