James N.C. Kew
GlaxoSmithKline (United Kingdom)(GB)
Publications by Year
Research Areas
Neuroscience and Neuropharmacology Research, Receptor Mechanisms and Signaling, Ion channel regulation and function, Nicotinic Acetylcholine Receptors Study, Neurotransmitter Receptor Influence on Behavior
Most-Cited Works
- → Ionotropic and metabotropic glutamate receptor structure and pharmacology(2005)777 cited
- → Ro 25–6981, a Highly Potent and Selective Blocker of N-Methyl-d-aspartate Receptors Containing the NR2B Subunit. Characterization in Vitro(1997)482 cited
- → Allosteric modulators of NR2B‐containing NMDA receptors: molecular mechanisms and therapeutic potential(2009)385 cited
- → A novel mechanism of activity‐dependent NMDA receptor antagonism describes the effect of ifenprodil in rat cultured cortical neurones.(1996)239 cited
- → Positive allosteric modulators of metabotropic glutamate 1 receptor: Characterization, mechanism of action, and binding site(2001)236 cited
- → Developmental Changes in NMDA Receptor Glycine Affinity and Ifenprodil Sensitivity Reveal Three Distinct Populations of NMDA Receptors in Individual Rat Cortical Neurons(1998)224 cited
- → PS2APP Transgenic Mice, Coexpressing hPS2mut and hAPPswe, Show Age-Related Cognitive Deficits Associated with Discrete Brain Amyloid Deposition and Inflammation(2003)200 cited
- → d‐Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia(2007)172 cited
- → Presynaptic α7- and β2-Containing Nicotinic Acetylcholine Receptors Modulate Excitatory Amino Acid Release from Rat Prefrontal Cortex Nerve Terminals via Distinct Cellular Mechanisms(2008)161 cited
- → Pharmacological manipulation of mGlu2 receptors influences cognitive performance in the rodent(2004)159 cited