Linghao Niu
La Roche College(US)
Publications by Year
Research Areas
Cytokine Signaling Pathways and Interactions, Immune Response and Inflammation, RNA modifications and cancer, Melanoma and MAPK Pathways, Quinazolinone synthesis and applications
Most-Cited Works
- → Metal Impurities Cause False Positives in High-Throughput Screening Campaigns(2012)119 cited
- → Deletion of the Escherichia coli pseudouridine synthase gene truB blocks formation of pseudouridine 55 in tRNA in vivo, does not affect exponential growth, but confers a strong selective disadvantage in competition with wild-type cells(2000)117 cited
- → Functional Effect of Deletion and Mutation of theEscherichia coli Ribosomal RNA and tRNA Pseudouridine Synthase RluA(1999)97 cited
- → 16S ribosomal RNA pseudouridine synthase RsuA of Escherichia coli: Deletion, mutation of the conserved Asp102 residue, and sequence comparison among all other pseudouridine synthases(1999)78 cited
- → Cutting Edge: IL-1 Receptor-Associated Kinase 4 Structures Reveal Novel Features and Multiple Conformations(2007)70 cited
- → 3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models(2012)66 cited
- → Pyrrolopyrazines as Selective Spleen Tyrosine Kinase Inhibitors(2013)39 cited
- → Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome(2013)33 cited
- → Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors(2013)32 cited
- → High-affinity binding to the GM-CSF receptor requires intact N-glycosylation sites in the extracellular domain of the β subunit(2000)30 cited