Kandasamy Pachamuthu
Wave Life Sciences (United States)(US)
Publications by Year
Research Areas
Carbohydrate Chemistry and Synthesis, Chemical Synthesis and Analysis, RNA and protein synthesis mechanisms, RNA Interference and Gene Delivery, Advanced biosensing and bioanalysis techniques
Most-Cited Works
- → Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing(2014)1,048 cited
- → Biodegradable Lipids Enabling Rapidly Eliminated Lipid Nanoparticles for Systemic Delivery of RNAi Therapeutics(2013)602 cited
- → An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia(2015)291 cited
- → Synthetic Routes to Thiooligosaccharides and Thioglycopeptides(2005)273 cited
- → siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in Hepatocytes(2015)207 cited
- → Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides(2022)108 cited
- → Antibacterial Aminoglycosides with a Modified Mode of Binding to the Ribosomal‐RNA Decoding Site(2004)98 cited
- → Ceric Ammonium Nitrate-Catalyzed Tetrahydropyranylation of Alcohols and Synthesis of 2-Deoxy-O-Glycosides(2001)85 cited
- → Variant-selective stereopure oligonucleotides protect against pathologies associated with C9orf72-repeat expansion in preclinical models(2021)84 cited
- → Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS(2022)68 cited