Francis P. Lach
Rockefeller University(US)
Publications by Year
Research Areas
DNA Repair Mechanisms, CRISPR and Genetic Engineering, Carcinogens and Genotoxicity Assessment, BRCA gene mutations in cancer, Epigenetics and DNA Methylation
Most-Cited Works
- → Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer(2006)641 cited
- → Mutations of the SLX4 gene in Fanconi anemia(2011)371 cited
- → A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair(2010)335 cited
- → Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency(2012)301 cited
- → FANCI is a second monoubiquitinated member of the Fanconi anemia pathway(2007)277 cited
- → A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination(2015)259 cited
- → FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair(2012)238 cited
- → Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4(2012)177 cited
- → Human GEN1 and the SLX4-Associated Nucleases MUS81 and SLX1 Are Essential for the Resolution of Replication-Induced Holliday Junctions(2013)147 cited
- → Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency(2017)140 cited