Michelle Ellis-Hutchings
United States Military Academy(US)
Publications by Year
Research Areas
Protein Kinase Regulation and GTPase Signaling, Peptidase Inhibition and Analysis, Microbial Natural Products and Biosynthesis, Ubiquitin and proteasome pathways, Click Chemistry and Applications
Most-Cited Works
- Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.(2001)
- → 3-Aminopyrrolidinone Farnesyltransferase Inhibitors: Design of Macrocyclic Compounds with Improved Pharmacokinetics and Excellent Cell Potency(2002)84 cited
- → Dual Protein Farnesyltransferase−Geranylgeranyltransferase-I Inhibitors as Potential Cancer Chemotherapeutic Agents(2003)60 cited
- → Design and Biological Activity of (S)-4-(5-{[1-(3-Chlorobenzyl)-2- oxopyrrolidin-3-ylamino]methyl}imidazol-1-ylmethyl)benzonitrile, a 3-Aminopyrrolidinone Farnesyltransferase Inhibitor with Excellent Cell Potency(2001)43 cited
- → Potent inhibitors of farnesyltransferase and geranylgeranyltransferase-I(2002)22 cited
- → The synthesis and biological evaluation of a series of potent dual inhibitors of farnesyl and geranyl-Geranyl protein transferases(2002)13 cited
- → Macrocyclic piperazinones as potent dual inhibitors of farnesyltransferase and geranylgeranyltransferase-I(2004)11 cited
- → Evaluation of amino acid-based linkers in potent macrocyclic inhibitors of farnesyl-protein transferase(2001)5 cited