Rob Howes
Publications by Year
Research Areas
Heat shock proteins research, Endoplasmic Reticulum Stress and Disease, Enzyme Structure and Function, ATP Synthase and ATPases Research, DNA Repair Mechanisms
Most-Cited Works
- → NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis(2008)476 cited
- → Identification of chemically diverse Chk1 inhibitors by receptor-based virtual screening(2006)362 cited
- → Novel Adenosine-Derived Inhibitors of 70 kDa Heat Shock Protein, Discovered Through Structure-Based Design(2009)222 cited
- → Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT)(2012)139 cited
- → Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity(2011)112 cited
- → Structure-Based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein−Ligand Affinity(2005)93 cited
- → Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: Protein structure-guided design and SAR(2005)69 cited
- → Structure-guided design of pyrazolo[1,5-a]pyrimidines as inhibitors of human cyclin-dependent kinase 2(2005)68 cited
- → Use of CRISPR/Cas9-engineered INS-1 pancreatic β cells to define the pharmacology of dual GIPR/GLP-1R agonists(2016)67 cited
- → A structure-based strategy to identify new molecular scaffolds targeting the bacterial ribosomal A-site(2004)57 cited