Edward P. Harvey
Harvard University(US)Boston VA Research Institute(US)
Publications by Year
Research Areas
Protein Degradation and Inhibitors, Peptidase Inhibition and Analysis, Monoclonal and Polyclonal Antibodies Research, Ubiquitin and proteasome pathways, Cell death mechanisms and regulation
Most-Cited Works
- → Selective Covalent Targeting of Anti-Apoptotic BFL-1 by Cysteine-Reactive Stapled Peptide Inhibitors(2016)80 cited
- → An in silico method to assess antibody fragment polyreactivity(2022)58 cited
- → Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization(2020)52 cited
- → Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor(2017)48 cited
- → Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering(2020)37 cited
- → Precision Targeting of BFL-1/A1 and an ATM Co-dependency in Human Cancer(2018)21 cited
- → A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes(2021)21 cited
- → Identification of a Structural Determinant for Selective Targeting of HDMX(2020)8 cited
- → Targeting a helix-in-groove interaction between E1 and E2 blocks ubiquitin transfer(2020)8 cited
- → Nanobodies targeting EGFR provide insight into conformations stabilized by glioblastoma mutations(2025)6 cited